Seasonal Variation in Vitamin D Status among Frail Older Hospitalized Patients.
J Frailty Aging. 2018;7(2):95-99. doi: 10.14283/jfa.2018.10.
Pourhassan M1, Wirth R.
Maryam Pourhassan, Department of Geriatric Medicine, Marien Hospital Herne, University Hospital, Ruhr-University Bochum, Germany, Hölkeskampring 40, D-44625 Herne, Germany, Tel: 023255937, Fax: 02323 - 499 - 3387, Email: maryam.pourhassan at ruhr-uni-bochum.de.
- Search VitaminDWiki for FRAILITY 513 items as of May 2019
- 80 percent of the characteristics of frailty associated with low vitamin D – May 2013
- Frailty risk increases 12 percent for every 10 ng less vitamin D – meta-analysis Sept 2018
- Frailty and Vitamin D - many studies
13 reasons why many seniors need more vitamin D (both dose and level) - July 2023 has the following
- Senior skin produces 4X less Vitamin D for the same sun intensity
- Seniors have fewer vitamin D receptor genes as they age
Receptors are needed to get Vitamin D in blood actually into the cells - Many other Vitamin D genes decrease with age
- Since many gene activations are not detected by a blood test,
more Vitamin D is often needed, especially by seniors - Seniors are indoors more than when they were younger
not as agile, weaker muscles; frail, no longer enjoy hot temperatures - Seniors wear more clothing outdoors than when younger
Seniors also are told to fear skin cancer & wrinkles - Seniors often take various drugs which end up reducing vitamin D
Some reductions are not detected by a vitamin D test of the blood
statins, chemotherapy, anti-depressants, blood pressure, beta-blockers, etc - Seniors often have one or more diseases that consume vitamin D
osteoporosis, diabetes, Multiple Sclerosis, Cancer, ... - Seniors generally put on weight as they age - and a heavier body requires more vitamin D
- Seniors often (40%) have fatty livers – which do not process vitamin D as well
- Reduced stomach acid means less Magnesium is available to get vitamin D into the cells
- Vitamin D is not as bioavailable in senior intestines
- Seniors with poorly functioning kidneys do not process vitamin D as well
- Glutathione (which increases Vitamin D getting to cells) decreases with age
Seniors category has430 items
BACKGROUND AND OBJECTIVES:
Seasonal variation in 25-hydroxyvitamin D [25(OH)D] levels is the result of sunlight dependent skin synthesis of vitamin D. However, its presence is not studied in frail older hospitalized patients. We sought to investigate whether seasonal variation in 25(OH)D levels is evident among these patients.DESIGN AND SETTING:
This study investigated older participants who were consecutively admitted between February 2015 and December 2016 to the geriatric acute care ward. Results of routine measurements of 25(OH)D at hospital admission were retrospectively analyzed and stratified according to months and seasons. Previous intake of vitamin D supplementation was derived from the patients' medical records.RESULTS:
The study group comprised 679 participants (mean age 82.1±8.2; 457 females), of which 78% had vitamin D deficiency. Older individuals not taking vitamin D supplements had a lower mean serum 25(OH)D than those receiving supplements. Of those patients with no vitamin D supplementation, 87.0% were vitamin D deficient and only 5% showing sufficient vitamin 25(OH)D. Further, there were neither monthly nor seasonal variations in vitamin 25(OH)D levels among these patients and their vitamin D levels stayed far below the recommended threshold of 20 ng/ml across the seasons.CONCLUSION:
Vitamin D deficiency was very prevalent in the subgroup of older hospitalized patients without vitamin D supplementation, irrespective of season. Since no seasonal variations in mean 25(OH)D levels was observed, sunlight dependent skin synthesis is unlikely to contribute to vitamin D status in these patients. Supplementation seems to be necessary to maintain desirable vitamin D levels among this population throughout the year.Majority of frail hospital patients had low vitamin D, which did not change with season – 2018Printer Friendly Follow this page for updates5806 visitors, last modified 24 May, 2019, This page is in the following categories (# of items in each category)